Plant Transcription Factor Database
Previous version: v3.0
Glycine soja
WOX Family
Species TF ID Description
KHN35694.1WOX family protein
KHN12799.1WOX family protein
KHN16235.1WOX family protein
KHN21965.1WOX family protein
KHN40312.1WOX family protein
KHN04484.1WOX family protein
KHN22335.1WOX family protein
KHN32118.1WOX family protein
KHN10543.1WOX family protein
KHN00156.1WOX family protein
KHN34739.1WOX family protein
KHN36395.1WOX family protein
KHN13077.1WOX family protein
KHN36039.1WOX family protein
KHN41901.1WOX family protein
KHN32229.1WOX family protein
KHN48164.1WOX family protein
KHN43009.1WOX family protein
KHN08070.1WOX family protein
KHN44615.1WOX family protein
KHN23724.1WOX family protein
KHN33396.1WOX family protein
KHN30986.1WOX family protein
KHN42185.1WOX family protein
KHN34632.1WOX family protein
KHN37332.1WOX family protein
KHN23140.1WOX family protein
KHN13883.1WOX family protein
KHN27215.1WOX family protein
KHN20105.1WOX family protein
KHN33793.1WOX family protein
KHN47208.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590